Could you check the "integrity" of file ed by sPortable 8.75.0.140 to unpack / install Skype (Skype-Setup.exe)?. Today - 2021-10-19, It is ed but failed when used to be unpacked / installed.
System: Windows 10 Pro
RAM: 8Gb
PAF Platform: 19
This will happen when a new version is released. You just need to let us know in the Outdated Apps Thread via the or Development pages. It's just been posted.
Sometimes, the impossible can become possible, if you're awesome!